Items in cart [0] Questions? Call 888-624-8373

PAPERBACK list:$42.75 Web:$38.48 add to cart PDF BOOK your price: $33.00 add to cart Rights & Permissions Free Resources PDF EXECUTIVE SUMMARY Display this book on your site! Related Titles Fluoride in Drinking Water: A Scientific Review of EPA's Standards Spacecraft Water Exposure Guidelines for Selected Contaminants: Volume 2 Other Related Titles Health Effects of Ingested Fluoride (1993) Commission on Life Sciences (CLS) Web Search Builder Use this book's key terms to search within this book, across our collection, or across the Web. Skim This Chapter Skim this chapter and use this chapter's key terms to search within this book. Reference Finder Paste in your own text to find books that relate to your topic. Page 173   E-mail  Facebook  Digg  Stumble  Twitter More Page 173 FRONT MATTER (R1-R18) EXECUTIVE SUMMARY (1-14) 1 INTRODUCTION (15-18) 2 DENTAL FLUOROSIS (19-50) 3 FLUORIDE EXPOSURE AND RISK OF BONE FRACTURE (51-72) 4 REPRODUCTIVE EFFECTS OF FLUORIDE (73-84) 5 EFFECTS OF INGESTED FLUORIDE ON RENAL, GASTROINTESTINAL, AND IMMUNE SYSTEMS (85-90) 6 GENOTOXICITY OF FLUORIDE (91-108) 7 CARCINOGENICITY OF FLUORIDE (109-124) 8 INTAKE, METABOLISM, AND DISPOSITION OF FLUORIDE (125-134) REFERENCES (135-166) APPENDIX 1 (167-172) APPENDIX 2 (173-176) APPENDIX 3 (177-181)

Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.

OCR for page 173
APPENDIX 2 LeHer to AF!P

OCR for page 174

OCR for page 175
Appendix 17S NATIONAL RESEARCH COUNCIL I3OARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY 2101 Co~lstittitio~l A`re~ll~t, Waslli~lytt,il, D.C. 20418 COM\lIT1 EE C)N' T(]XICOI OGY Colonel John M. Pletcher Department of Veterinary Pathology Armed Forces Institute of Pathology Washington, DC 20306-6000 Dear Col. Pletcher: July 24, 1992 The National Research Council's Committee on Toxicology has organized the Subcommittee on Risk Assessment of Ingested Fluoride. This study was requested by the U.S. Environmental Protection Agency to determine if the current drinking water standard for fluoride (4 mg/L) is appropriate. At its second meeting on July 13, 1992, in Aspen, CO, the subcommittee recommended the review of Procter and Gamble's mouse fluoride carcinogenicity study by the Armed Forces Institute of Pathology (AFIP) for the following: What is the proper terminology for these lesions? Should the osteomas be considered neoplasms? Is there a hyperostosis/osteoma continuum? Do the osteomas have potential for malignant change? Would these lesions regress if the stimulus were removed? How often are bone neoplasms in animals multicentric? Is there a human counterpart for these lesions? Of those people involved, there is general knowledge of a contaminating virus in this mouse study. What evidence is available to confirm it? We have requested Procter and Gamble to submit mouse slides to AFIP for its independent review. The final meeting of the subcommittee is scheduled for October 16, 1992, in Washington, DC. Therefore, it would be helpful if you could review the slides as soon as possible and have your report prior to the October 16 meeting. Tl/i .\t,~ti`~n,71 RL'S{'/7/ t l/ Ct,nn~-il is flu I,/ in. i/,,71 t4','n7tin< /7g`'n~!/ Of tl/t .N',itit,nal .Ai ,7,1, A/!/ t,! St it nt ~ s ,7/u{ flu ,~,?tit,n,rl . l.-.7,z~ A/!/ (]f hngint ~ / ing try se/ At gr7Z'r'/ n'ut'ut 0/u1 title/ t7/guni:atit,'/s. Tin- Bi,,7/,1 fin C//z~i/ t7/nut nti71 Stu`lit s ,7/ul Try rit t~li'V!/ ii n sl ~i,n5il~lt try tall- N/,7titinu1 Rt st,7/ i-l/ Ci7/n~-il tin t'ugl/ flu- Ct,/innissli,n 4~// 1.//r Stit //t-t s ,7//~1 tl/t Cti,/////iisi`~// If// Gi fist it 'rt ~ s. F//;'i/,',////t lit. `~//,1 Rt sti///-t ~ s. TEI: (2()2) 334-26]6 I:AX: (2()2) 334-1393

OCR for page 176
176 Health Effects of Ingested Fluoride We highly appreciate your willingness to review the mouse slides for us. With best regards, I am, Sincerely, kin ~ F:~ Kulbir S. Bakshi, Ph.D. Project Director KSB/cmk

Representative terms from entire chapter:

ingested fluoride